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Key strategies for reducing spread of avian influenza among commercial poultry holdings: lessons for transmission to humans

Identifieur interne : 000A29 ( France/Analysis ); précédent : 000A28; suivant : 000A30

Key strategies for reducing spread of avian influenza among commercial poultry holdings: lessons for transmission to humans

Auteurs : Arnaud Le Menach [France] ; Elisabeta Vergu [France] ; Rebecca F. Grais [France] ; David L. Smith [États-Unis] ; Antoine Flahault [France]

Source :

RBID : ISTEX:656D44444E0223500980FEEC2902EFF7A5C2185F

Descripteurs français

English descriptors

Abstract

Recent avian flu epidemics (A/H5N1) in Southeast Asia and case reports from around the world have led to fears of a human pandemic. Control of these outbreaks in birds would probably lead to reduced transmission of the avian virus to humans. This study presents a mathematical model based on stochastic farm-to-farm transmission that incorporates flock size and spatial contacts to evaluate the impact of control strategies. Fit to data from the recent epidemic in the Netherlands, we evaluate the efficacy of control strategies and forecast avian influenza dynamics. Our results identify high-risk areas of spread by mapping of the farm level reproductive number. Results suggest that an immediate depopulation of infected flocks following an accurate and quick diagnosis would have a greater impact than simply depopulating surrounding flocks. Understanding the relative importance of different control measures is essential for response planning.

Url:
DOI: 10.1098/rspb.2006.3609


Affiliations:


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ISTEX:656D44444E0223500980FEEC2902EFF7A5C2185F

Le document en format XML

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   |flux=    France
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   |type=    RBID
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   |texte=   Key strategies for reducing spread of avian influenza among commercial poultry holdings: lessons for transmission to humans
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